fig3
From: RIP140 regulates POLK gene expression and the response to alkylating drugs in colon cancer cells
Figure 3. Correlation of RIP140 and POLK gene expression in human CRC samples. (A) Analysis of RIP140 and POLK correlation using the mRNAs expression from the Cancertool database in the GSE39582 cohort[31]. The correlation coefficient and the p-value (Pearson’s test) are indicated. (B) Same as in (A) with the cohort GSE42284[32]. (C) Correlations between RIP140 and POLK gene expression performed with TCGA RNA-Seq cohort (n = 415)[4] showing the correlations found in the different CRC molecular subtypes described in this cohort. (D) Correlation between POLK and RIP140 gene expression in a cohort comparing the expression of “DNA replication” genes in CRC and in the adjacent normal mucosa (n = 26)[35].
