REFERENCES
1. Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin 2015;65:87-108.
2. Peltomäki P, Vasen HF. Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. Gastroenterology 1997;113:1146-58.
3. Ligtenberg MJ, Kuiper RP, Chan TL, et al. Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3’ exons of TACSTD1. Nat Genet 2009;41:112-7.
4. Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-7.
5. Carethers JM, Stoffel EM. Lynch syndrome and lynch syndrome mimics: the growing complex landscape of hereditary colon cancer. World J Gastroenterol 2015;21:9253-61.
7. Hile SE, Wang X, Lee MY, Eckert KA. Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability. Nucleic Acids Res 2012;40:1636-47.
8. Stancel JN, McDaniel LD, Velasco S, et al. Polk mutant mice have a spontaneous mutator phenotype. DNA Repair (Amst) 2009;8:1355-62.
9. Washington MT, Carlson KD, Freudenthal BD, Pryor JM. Variations on a theme: eukaryotic Y-family DNA polymerases. Biochim Biophys Acta 2010;1804:1113-23.
10. Lone S, Townson SA, Uljon SN, et al. Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. Mol Cell 2007;25:601-14.
11. Lupari E, Ventura I, Marcon F, et al. Pol kappa partially rescues MMR-dependent cytotoxicity of O6-methylguanine. DNA Repair (Amst) 2012;11:579-86.
12. Lv L, Wang F, Ma X, et al. Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation. Nucleic Acids Res 2013;41:10312-22.
13. Cavailles V, Dauvois S, L’Horset F, et al. Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J 1995;14:3741-51.
14. Augereau P, Badia E, Carascossa S, et al. The nuclear receptor transcriptional coregulator RIP140. Nucl Recept Signal 2006;4:e024.
15. Docquier A, Harmand PO, Fritsch S, et al. The transcriptional coregulator RIP140 represses E2F1 activity and discriminates breast cancer subtypes. Clin Cancer Res 2010;16:2959-70.
16. Zschiedrich I, Hardeland U, Krones-Herzig A, et al. Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression. Blood 2008;112:264-76.
17. Castet A, Boulahtouf A, Versini G, et al. Multiple domains of the receptor-interacting protein 140 contribute to transcription inhibition. Nucleic Acids Res 2004;32:1957-66.
18. Yang XJ, Seto E. Lysine acetylation: codified crosstalk with other posttranslational modifications. Mol Cell 2008;31:449-61.
19. White R, Leonardsson G, Rosewell I, et al. The nuclear receptor co-repressor nrip1 (RIP140) is essential for female fertility. Nat Med 2000;6:1368-74.
20. Nautiyal J, Steel JH, Mane MR, et al. The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development 2013;140:1079-89.
21. Leonardsson G, Steel JH, Christian M, et al. Nuclear receptor corepressor RIP140 regulates fat accumulation. Proc Natl Acad Sci U S A 2004;101:8437-42.
22. Ho PC, Tsui YC, Feng X, Greaves DR, Wei LN. NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance. Nat Immunol 2012;13:379-86.
23. Duclot F, Lapierre M, Fritsch S, et al. Cognitive impairments in adult mice with constitutive inactivation of RIP140 gene expression. Genes Brain Behav 2012;11:69-78.
24. Lapierre M, Bonnet S, Bascoul-Mollevi C, et al. RIP140 increases APC expression and controls intestinal homeostasis and tumorigenesis. J Clin Invest 2014;124:1899-913.
25. Gleizes A, Triki M, Bonnet S, et al. RIP140 represses intestinal paneth cell differentiation and interplays with SOX9 signaling in colorectal cancer. Cancers (Basel) 2021;13:3192.
26. Palassin P, Lapierre M, Pyrdziak S, et al. A truncated NRIP1 mutant amplifies microsatellite instability of colorectal cancer by regulating MSH2/MSH6 expression, and is a prognostic marker of stage III tumors. Cancers (Basel) 2021;13:4449.
27. Jalaguier S, Teyssier C, Nait Achour T, et al. Complex regulation of LCoR signaling in breast cancer cells. Oncogene 2017;36:4790-801.
28. Zilliacus J, Holter E, Wakui H, et al. Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140. Mol Endocrinol 2001;15:501-11.
29. Lemée F, Bavoux C, Pillaire MJ, et al. Characterization of promoter regulatory elements involved in downexpression of the DNA polymerase kappa in colorectal cancer. Oncogene 2007;26:3387-94.
30. Rácz GA, Nagy N, Tóvári J, Apáti Á, Vértessy BG. Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines. Sci Rep 2021;11:19459.
31. Marisa L, de Reyniès A, Duval A, et al. Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value. PLoS Med 2013;10:e1001453.
32. Roepman P, Schlicker A, Tabernero J, et al. Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition. Int J Cancer 2014;134:552-62.
33. Cortazar AR, Torrano V, Martín-Martín N, et al. CANCERTOOL: a visualization and representation interface to exploit cancer datasets. Cancer Res 2018;78:6320-8.
34. Salazar R, Roepman P, Capella G, et al. Gene expression signature to improve prognosis prediction of stage II and III colorectal cancer. J Clin Oncol 2011;29:17-24.
35. Pillaire MJ, Selves J, Gordien K, et al. A ‘DNA replication’ signature of progression and negative outcome in colorectal cancer. Oncogene 2010;29:876-87.
36. Nagy Á, Munkácsy G, Győrffy B. Pancancer survival analysis of cancer hallmark genes. Sci Rep 2021;11:6047.
37. Györffy B, Lanczky A, Eklund AC, et al. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. Breast Cancer Res Treat 2010;123:725-31.
38. Augereau P, Badia E, Balaguer P, et al. Negative regulation of hormone signaling by RIP140. J Steroid Biochem Mol Biol 2006;102:51-9.
39. Castet A, Herledan A, Bonnet S, et al. Receptor-interacting protein 140 differentially regulates estrogen receptor-related receptor transactivation depending on target genes. Mol Endocrinol 2006;20:1035-47.
40. Wang Y, Seimiya M, Kawamura K, et al. Elevated expression of DNA polymerase kappa in human lung cancer is associated with p53 inactivation: Negative regulation of POLK promoter activity by p53. Int J Oncol 2004;25:161-5.
41. Wit N, Buoninfante OA, van den Berk PC, et al. Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage. Nucleic Acids Res 2015;43:282-94.
42. Ogi T, Mimura J, Hikida M, Fujimoto H, Fujii-Kuriyama Y, Ohmori H. Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription. Genes Cells 2001;6:943-53.
43. Madak-Erdogan Z, Katzenellenbogen BS. Aryl hydrocarbon receptor modulation of estrogen receptor α-mediated gene regulation by a multimeric chromatin complex involving the two receptors and the coregulator RIP140. Toxicol Sci 2012;125:401-11.
44. Wei LN, Hu X, Chandra D, Seto E, Farooqui M. Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing. J Biol Chem 2000;275:40782-7.
45. Friedberg EC. Suffering in silence: the tolerance of DNA damage. Nat Rev Mol Cell Biol 2005;6:943-53.
46. Bétous R, Pillaire MJ, Pierini L, et al. DNA polymerase κ-dependent DNA synthesis at stalled replication forks is important for CHK1 activation. EMBO J 2013;32:2172-85.
47. Wang H, Wu W, Wang HW, et al. Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance. Neuro Oncol 2010;12:679-86.
48. Bavoux C, Leopoldino AM, Bergoglio V, et al. Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cancer Res 2005;65:325-30.
49. Allera-Moreau C, Rouquette I, Lepage B, et al. DNA replication stress response involving PLK1, CDC6, POLQ, RAD51 and CLASPIN upregulation prognoses the outcome of early/mid-stage non-small cell lung cancer patients. Oncogenesis 2012;1:e30.
50. Pan Q, Fang Y, Xu Y, Zhang K, Hu X. Down-regulation of DNA polymerases kappa, eta, iota, and zeta in human lung, stomach, and colorectal cancers. Cancer Lett 2005;217:139-47.
