Cancer Drug Resistance

Advances in preclinical evaluation of experimental antibody-drug conjugates

Scott K. Lyons, Dennis Plenker, Lloyd C. Trotman

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Page 745-754
Tackling cisplatin resistance in ovarian cancer: what can we do?

Paola Perego

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Page 755-757
Targeting DNA topoisomerases: past & future

William H. Gmeiner, Robert C. A. M. van Waardenburg

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Page 758-761
Experimental models of endocrine responsive breast cancer: strengths, limitations, and use

Robert Clarke, Brandon C. Jones, Catherine M. Sevigny, Leena A. Hilakivi-Clarke, Surojeet Sengupta

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Page 762-783
The roles of the human ATP-binding cassette transporters P-glycoprotein and ABCG2 in multidrug resistance in cancer and at endogenous sites: future opportunities for structure-based drug design of inhibitors

Jason Goebel, Jean Chmielewski, Christine A. Hrycyna

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Page 784-804
Notch signaling in female cancers: a multifaceted node to overcome drug resistance

Maria V. Giuli, Angelica Mancusi, Eugenia Giuliani, Isabella Screpanti, Saula Checquolo

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Page 805-836
Targeting DNA repair pathways to overcome cancer drug resistance

Robert C.A.M. van Waardenburg, Eddy S. Yang

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Page 837-841
MYC inhibitors in multiple myeloma

Sandra Martínez-Martín, Laura Soucek

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Page 842-865
The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres

Seung-Hun Kim, Po-Wei Fan, Chang-Heng Hsieh, Hsuan-Yuan Lin, Wen-Hsin Wang, Ming-Chung Lee, Kang Fang

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Page 866-880
Overcoming acquired chemo-resistance to gemcitabine: implications from the perspective of multi-modal therapy including surgery for pancreatic cancer

Fuyuhiko Motoi

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Page 881-884
Recent advances in tumor-targeting chemotherapy drugs

Iwao Ojima

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Page 885-887
Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat

Tiewei Cheng, Kendall Kiser, Leslie Grasse, Lakesla Iles, Geoffrey Bartholomeusz, Felipe Samaniego, Robert Z. Orlowski, Joya Chandra

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Page 888-902
Erratum: P53-regulated autophagy and its impact on drug resistance and cell fate

Daeun Shim, Lei Duan, Carl G. Maki

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Page 903-
SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance

Ornella Randazzo, Stella M. Cascioferro, Camilla Pecoraro, Widad Ait Iddouch, Amir Avan, Barbara Parrino, Daniela Carbone, Ugo Perricone, Godefridus J. Peters, Patrizia Diana, Elisa Giovannetti

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Page 904-922
The HGF/c-MET axis as a potential target to overcome survival signals and improve therapeutic efficacy in multiple myeloma

Paolo Giannoni, Daniela de Totero

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Page 923-933
Overview of microRNAs as liquid biopsy biomarkers for colorectal cancer sub-type profiling and chemoresistance

Alfred Buhagiar, Elisa Seria, Miriana Borg, Joseph Borg, Duncan Ayers

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Page 934-945
Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review

Shogo Ozawa, Toshitaka Miura, Jun Terashima, Wataru Habano

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Page 946-964
Barriers to achieving a cure in lymphoma

Swetha Kambhampati, Joo Y. Song, Alex F. Herrera, Wing C. Chan

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Page 965-983
Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance

Montserrat Estruch, Camilla Vittori, Teresa Muñoz Montesinos, Kristian Reckzeh, Kim Theilgaard-Mönch

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Page 984-995
Adjuvant role of a T-type calcium channel blocker, TTA-A2, in lung cancer treatment with paclitaxel

Neema Kumari, Pravin Shankar Giri, Subha Narayan Rath

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Page 996-1007
Gene expression profiling as a prognostic tool in multiple myeloma

Harmony Black, Siobhan Glavey

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Page 1008-1017
EGFR/BRAF/MEK co-inhibition for EGFR-mutated lung adenocarcinoma patients with an acquired BRAF^V600E mutation: a case report and review of literature

Ran Zeng, Lifeng Luo, Xianwen Sun, Zhiyao Bao, Wei Du, Ranran Dai, Wei Tang, Beili Gao, Yi Xiang

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Page 1018-1026
Overcoming drug resistance by targeting protein homeostasis in multiple myeloma

Maria Moscvin, Matthew Ho, Giada Bianchi

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Page 1027-1045

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Table of Contents (23 articles)

Advances in preclinical evaluation of experimental antibody-drug conjugates

Tackling cisplatin resistance in ovarian cancer: what can we do?

Targeting DNA topoisomerases: past & future

Experimental models of endocrine responsive breast cancer: strengths, limitations, and use

The roles of the human ATP-binding cassette transporters P-glycoprotein and ABCG2 in multidrug resistance in cancer and at endogenous sites: future opportunities for structure-based drug design of inhibitors

Notch signaling in female cancers: a multifaceted node to overcome drug resistance

Targeting DNA repair pathways to overcome cancer drug resistance

MYC inhibitors in multiple myeloma

The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres

Overcoming acquired chemo-resistance to gemcitabine: implications from the perspective of multi-modal therapy including surgery for pancreatic cancer

Recent advances in tumor-targeting chemotherapy drugs

Expression of histone deacetylase (HDAC) family members in bortezomib-refractory multiple myeloma and modulation by panobinostat

Erratum: P53-regulated autophagy and its impact on drug resistance and cell fate

SF3B1 modulators affect key genes in metastasis and drug influx: a new approach to fight pancreatic cancer chemoresistance

The HGF/c-MET axis as a potential target to overcome survival signals and improve therapeutic efficacy in multiple myeloma

Overview of microRNAs as liquid biopsy biomarkers for colorectal cancer sub-type profiling and chemoresistance

Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review

Barriers to achieving a cure in lymphoma

Targeting of PI3K/AKT signaling and DNA damage response in acute myeloid leukemia: a novel therapeutic strategy to boost chemotherapy response and overcome resistance

Adjuvant role of a T-type calcium channel blocker, TTA-A2, in lung cancer treatment with paclitaxel

Gene expression profiling as a prognostic tool in multiple myeloma

EGFR/BRAF/MEK co-inhibition for EGFR-mutated lung adenocarcinoma patients with an acquired BRAF^V600E mutation: a case report and review of literature

Overcoming drug resistance by targeting protein homeostasis in multiple myeloma

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