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Topic: Cell Cycle-based Therapies to Overcome Chemoresistance

A special issue of Cancer Drug Resistance

ISSN 2578-532X (Online)

Submission deadline: 31 Dec 2021

Guest Editor(s)

  • Dr. Ilana Chefetz, PhD
    The Hormel Institute, University of Minnesota, Austin, MN, USA.

    Website | E-mail

  • Dr. Akimasa Takahashi, MD, PhD
    The Hormel Institute, University of Minnesota, Austin, MN, USA.

    Website | E-mail

  • Dr.Imran Khan, PhD
    The Hormel Institute, University of Minnesota, Austin, MN, USA.

    Website | E-mail

Special Issue Introduction

Dear colleagues,

Development of chemoresistance is one of the biggest problems in cancer causing recurrent disease and metastasis. Thus, it is crucial to elucidate molecular mechanisms and signaling pathways to develop novel targeted therapies to overcome chemoresistance.

Cell cycle abnormalities are a hallmark of cancer. The major players of the cell cycle machinery are the cyclin-dependent kinases (CDK) and the regulatory proteins called cyclins. CDK inhibitors exhibit promising results in preclinical studies blocking cell proliferation and causing cell death.

For this special issue we would like to invite original research and clinical manuscripts as well as updated reviews discussing cell cycle aberrations in cancer and novel targeted therapies that inhibit cell cycle regulators. Moreover, topics also include comparison of cell cycle inhibitors as single agents or in combination with cytotoxic drugs. In addition, this special issue will focus on the effect of CDK inhibitors on tumor microenvironment and cancer stem cells.  Finally, we would like to highlight novel cell cycle-based therapies in clinical trials and combination strategies that will improve disease-free and total survival.

Looking forward to your contributions.

Submission Deadline

31 Dec 2021

Submission Information

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to http://cdrjournal.com/pages/view/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=cdr&SpecialIssueId=700
Submission Deadline: 31 Dec 2021
Contacts: Susan Song, Assistant Editor, Susan@cdrjournal.com

Published Articles

This special issue is now open for submission.
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