Top
Topic: New challenges in overcoming chemoresistance in Glioblastoma

A special issue of Cancer Drug Resistance.

ISSN 2578-532X (Online)

Submission deadline: 30 Apr 2020

Guest Editor(s)

  • Chiara Riganti, MD
    Associate professor of biochemistry, Oncological Pharmacology Lab, Department of Oncology, University of Torino, via Santena 5/bis, 10126 Torino, Italy

    Website | E-mail

  • Joanna Kopecka, PhD
    Assistant professor of biochemistry, Oncological Pharmacology Lab, Department of Oncology, University of Torino, 10126 Torino, Italy

    Website | E-mail

Special Issue Introduction

Despite the recent improvements in our knowledge on glioblastoma genotype and the enlarged spectrum of drugs and drug delivery-technologies developed for glioblastoma, the overall survival of patients with this tumor has not improved in the last years. Chemoresistance can be due to tumor intrinsic factors, mainly related to specific alterations in genotypic, epigenetic and miRNOME profile, or to extrinsic factors, such as the presence of blood-brain barrier and hypoxic niches, that favor the growth of chemoresistant stem cells. Identifying new biomarkers that stratify patients in responders or non-responders to pharmacological therapies, as well as finding innovative strategies improving drug delivery and drug efficacy, are two unmet needs in the current approach to the diagnosis and treatment of this tumor.
This Special Issue will provide an overview of the latest discoveries in terms of biomarkers identification, chemoresistance mechanisms, chemosensitizing strategies for glioblastoma.

Keywords

Glioblastoma; chemoresistance; glioblastoma stem cells; blood-brain barrier; ABC transporters; miRNAs; tyrosine kinase receptors inhibitors; anti-angiogenic drugs; convection-enhanced delivery; nanocarriers

Submission Deadline

30 Apr 2020

Submission Information

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to http://cdrjournal.com/pages/view/author_instructions
For Online Submission, please login at https://www.oaemesas.com/cdr
Submission Deadline: 30 Apr 2020
Contacts: Ms. Belinda Zhang, Assistant Editor, editor_5@oaepublish.com

Published Articles

This special issue is now open for submission.