- Prof. Francois-Xavier Claret
- Department of Systems Biology, Division of Basic Science Research, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
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Special Issue Introduction
MicroRNAs (miRNAs) have been identified to be key players in health and disease which are deregulated in cancer which can influence the development of resistance to treatment. This special issue summarizes recent advances on the impact of miRNAs on therapy resistance in cancer and highlights how miRNA expression profiles can predict clinical outcome in cancer. Finally, we will provide an overview of the challenges of miRNA-targeted therapies for reversing drug resistance to sensitize tumor cells to chemotherapy, radiotherapy, and targeted treatment.
KeywordsmiRNA, lncRNA, resistance, expression profile, Network, predictive biomarker, miR signature, tumorigenesis, therapy
Submission Deadline31 Mar 2019