fig4

Figure 4. CB17 Scid mice are suitable hosts for SC263-R HNSCC cells when co-injected with 25% Matrigel. (A and B) Tumor kinetics over time after s.c. injection with 1 × 10⁶ SC263-R cells in CB17 Scid: (A) and BALB/c nude; (B) mice (n = 3); (C and D) Tumor kinetics over time after s.c. injection with 1 × 10⁶ SC263-R cells mixed with 25% Matrigel in CB17 Scid: (C) and BALB/c nude; (D) mice (n = 3). Each line represents the data of one individual mouse. HNSCC: Head and neck squamous cell carcinoma; -R: cetuximab-resistant HNSCC cell line; -S: cetuximab-sensitive HNSCC cell line; s.c.: subcutaneous.