fig8
From: Circular RNA circNCOA3 promotes tumor progression and anti-PD-1 resistance in colorectal cancer
Figure 8. Working model of the mechanism of circNCOA3 on CRC progression and PD-1 antibody treatment resistance. CircNCOA3 acts as a ceRNA by competitively sponging miR-203a-3p.1 to regulate the levels of CXCL1 and modulate the proliferation, invasion, and immune evasion of CRC cells. CRC: Colorectal cancer; PD-1: programmed cell death 1; ceRNA: competing endogenous RNA.
