fig1
From: Targeting metabolic vulnerabilities to overcome resistance to therapy in acute myeloid leukemia
Figure 1. List of clinical trials for metabolic inhibitors in AML. AML: Acute myeloid leukemia; ClpP: caseinolytic protease proteolytic subunit; CMML: chronic myelomonocytic leukemia; DHODH: dihydroorotate dehydrogenase; ETC: electron transport chain; IDH: isocitrate dehydrogenase enzyme; MDS: myelodysplastic syndromes; OXPHOS: oxidative phosphorylation; TCA: tricarboxylic acid cycle.
