fig5

Figure 5. A butein-instigated increase of miR-186-5p modulated oxidative mitochondrial respiration and glycolytic activity of MPM cells. (A, B) Basal ECAR and OCR measured in NCI-H2373 cells treated or transfected as indicated. Values are reported as mpH/min for ECAR and pmoles/min for OCR Results are shown as the mean ± SEM of three independent experiments. Asterisk indicate statistical significance as follows: *P < 0.05, **P < 0.01). (C) OCR to ECAR ratio assessed for all three MPM cell lines of this study.