fig1

Figure 1. Acquired HER2 alterations in patients with endocrine resistance. The location of HER2 alterations identified by sequencing metastatic biopsies is depicted along the length of the protein. Protein domains are indicated by colour coding. Evolutionary classification for alterations: red triangles, acquired alterations; blue triangles, alterations shared with primary tumour; grey triangles, indeterminate or unknown. Figure 1 and legend used from Nayar et al.^[13].