Figure6

Multicellular biomarkers of drug resistance as promising targets for glioma precision medicine and predictors of patient survival

Figure 6. Evaluation of the predictive performance of the identified signature in the proneural subtype of GBM: (A) time-dependent ROC curves with corresponding AUCs at one and two years in training set (TCGA, $$ n = $$ 38); (B) time-dependent ROC curves with corresponding AUCs at one and two years in testing set (CGGA, $$ n = $$ 30); (C) KM curves for high-risk and low-risk patients in training set; and (D) KM curves for high-risk and low-risk patients in testing set. $$ P $$-values were calculated from the log-rank test. TCGA: The Cancer Genome Atlas. CGGA: Chinese Glioma Genome Atlas. ROC: receiver operating characteristic. GBM: glioblastoma multiforme. KM: Kaplan-Meier.

Cancer Drug Resistance
ISSN 2578-532X (Online)

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