fig1

Figure 1. Resistance mechanisms to immunotherapy in soft tissue sarcoma with current treatment mechanisms aimed at overcoming resistance. ICI: Immune checkpoint inhibitor; MDSCs: myeloid-derived suppressor cells; MHC: major histocompatibility complex; PD-1: programmed cell death 1; TAMs: tumor-associated macrophages; TCR: T cell receptor; TKI: tyrosine kinase inhibitor; TME: tumor MIcroenvironment.