fig3

Figure 3. Acoustic angiography images of angiogenesis and vessel tortuosity. (A) Images of control non-tumor bearing regions and (B) fibrosarcoma tumor bearing regions in a rat. Tumor size is represented with dashed yellow lines. Tortuous vessels denoted by red arrows represent angiogenesis around the periphery of the tumor. Higher vascular density in the tumor is demonstrated by more enhancement in the images due to higher contrast agent perfusion. The vasculature in control images is more linear and directional, as shown. Figure reproduced with permission from^[217].