fig6

EGFR signaling promotes resistance to CHK1 inhibitor prexasertib in triple negative breast cancer

Figure 6. EGF stimulation in MDA-231 increased BAD phosphorylation. MDA-231 cells treated with vehicle, 20 nmol/L prexasertib, 50 nmol/L EGF, or both 50 nmol/L EGF and 20 nmol/L prexasertib were examined after 48 h of exposure. AKT: protein kinase B; EGF: epidermal growth factor; EGFR: epidermal growth factor receptor

Cancer Drug Resistance
ISSN 2578-532X (Online)

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