fig2

Resistance to second generation antiandrogens in prostate cancer: pathways and mechanisms

Figure 2. Distinct gene expression pattern of LNCaP-enzalutamide resistant cells in relation to AR. LNCaP cells treated with antiandrogen enzalutamide to generate LNCaP-enzalutamide resistant cells. These resistant cells show distinct gene expressed pattern in relation of AR in nucleus, cytoplasm, plasma membrane, and extracellular space. The red color shows increased expression, pink color shows less expression whereas green color shows decreased expression. The blue arrowhead shows genes leads to inhibition, while orange color shows gene leads to activation, while the dotted line shows its indirect interaction. AR: androgen receptor

Cancer Drug Resistance
ISSN 2578-532X (Online)

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