fig2

Therapeutic modulation of the CD47-SIRPα axis in the pediatric tumor microenvironment: working up an appetite

Figure 2. CD47 across pediatric histologies. For comparison, we included the top two adult expressing tumor types (ovarian serous cystadenocarcinoma and lung adenocarcinoma). For those histologies that are shared between pediatric and adults (e.g., acute lymphoblastic leukemia, acute megakaryoblastic leukemia, acute myeloid leukemia, adrenocortical carcinoma, glioblastoma multiforme, and glioma), we only included cases under age 19; for those histologies that are classically a pediatric diagnosis (all others), we included all ages to capture data in young adults with pediatric diagnoses as well. We only included histologies with at least 2 patient samples. We ordered the data by their average normalized expression. Y-axis represents log2 normalized or log2(TPM + 1) expression of CD47.. X-axis shows the diseases with the number of observations in parentheses

Cancer Drug Resistance
ISSN 2578-532X (Online)

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