fig1
From: Predictive value of exosomes and their cargo in drug response/resistance of breast cancer patients
Figure 1. A: Breast cancer comprises four subtypes defined by the positive (+) and negative (-) status of the ER, PR, and HER2; B: The breast cancer cell is positive for all three receptors. Cell proliferation is controlled by the ER and HER2 and is inhibited by the competitive binding of either fulvestrant or tamoxifen to the ER or trastzumab to HER2. ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2
