fig7
From: Use of MRI, metabolomic, and genomic biomarkers to identify mechanisms of chemoresistance in glioma
Figure 7. Effect of BCNU exposure to 9L rat glioma cells. Cells were exposed to 150 µM (9L-R1) or 225 µM (9L-R2) in culture or in vivo (9L-R3) after intracranial implantation (26.6 mg/kg body weight). RNA was subjected to 12-plex microarray to determine changes in gene expression compared to drug naïve cells (9L-S). Venn diagram illustrates the number of genes differentially regulated (P ≤ 0.05) in each of the three BCNU-resistant cell lines
