fig2

Molecular bases of Sorcin-dependent resistance to chemotherapeutic agents

Figure 2. A: In human sorcin, upon calcium binding, the conformational change determines exposure of hydrophobic residues, that are able to bind ligands; B: in the X-ray crystal structure of sorcin, part of the hydrophobic N-terminal domain (brown) results bound to residues of the D-helix

Cancer Drug Resistance
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