fig7

Reduction of mitomycin C resistance in human bladder cancer T24 cells by knocking-down ras oncogene

Figure 7. The incidence of Ki-67 labelled T24 cells as seen with different treatments. (A) Untreated cells; (B and C) cells treated with 3 and 10 μg/mL MMC, respectively, after 24 h; (D, E, and F) cells treated with 0.3, 3, and 10 μg/mL MMC, respectively after 72 h. The percentage of Ki-67 labelled cells (arrows) decreased progressively with increasing dose and duration of MMC treatment; (G, H, and I) cells treated with 0.3, 3, and 10 μg/mL MMC combined with 50 nmol/L ras siRNA after 72 h. The decrease in Ki-67 positivity was higher than with MMC alone (200×). MMC: mitomycin C

Cancer Drug Resistance
ISSN 2578-532X (Online)

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