fig1
From: Reduction of mitomycin C resistance in human bladder cancer T24 cells by knocking-down ras oncogene
Figure 1. Morphology of T24 cells as seen with different treatments. (A) Untreated cells; (B and C) cells treated with 3 and 30 μg/mL MMC respectively after 24 h; (D) cells treated with 0.3 μg/mL MMC after 72 h; (E and F) cells treated with 3 and 30 μg/mL MMC after 72 h; (G) cells treated with negative control ras siRNA after 72 h; (H and I) cells transfected with 50 and 100 nmol/L ras siRNA after 72 h, respectively. The cells became larger with loss of spindling. The architecture was significantly disrupted with marked decrease in cellularity; (J, K and L) cells treated with 0.3, 3, and 10 μg/mL MMC, respectively, combined with 50 nmol/L ras siRNA after 72 h. The arrows indicate apoptotic cells (Giemsa 400×). MMC: mitomycin C
