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Topic: Autophagy in Cancer and Therapy Resistance

A special issue of Cancer Drug Resistance

ISSN 2578-532X (Online)

Submission deadline: 20 May 2023

Guest Editor(s)

  • Prof. Ciro Isidoro
    Laboratory of Molecular Pathology and NanoBioImaging, Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy.

    Website | E-mail

  • Dr. Alessandra Ferraresi

    Laboratory of Molecular Pathology and NanoBioImaging, Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy.

    Website | E-mail

Special Issue Introduction

Autophagy is a lysosomal-driven catabolic process devoted to macromolecular turnover and intracellular homeostasis by recycling cytoplasmic constituents to sustain cell metabolism. De-regulation of autophagy has been recognized as one of the main metabolic features of cancer cells subjected to changes in the tumor microenvironment in terms of nutrients, oxygen, growth factors, cytokines and non-coding RNAs. Autophagy plays a dual role in carcinogenesis: it can contribute to carcinogenesis by sustaining the metabolic demands of cancer cells or by protecting them from harsh conditions and DNA damage, while hyper-induction of autophagy may lead to autophagic cell death, an alternative pathway to apoptosis that could be exploited for overcoming chemoresistance.
In this Special Issue, we welcome submissions of original research and review articles highlighting the functional role of autophagy in preventing and mitigating cancer. Particular emphasis will be on the biochemical/epigenetic/cellular mechanisms of autophagy modulation and to evaluate its interplay with the chemoresponse which crucially influences the success of anti-cancer therapies.

Submission Deadline

20 May 2023

Submission Information

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to http://cdrjournal.com/pages/view/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=cdr&SpecialIssueId=CDR221118
Submission Deadline: 20 May 2023
Contacts: Belinda Zhang, Assistant Editor, Belinda@cdrjournal.com

Published Articles

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