Hot Keywords
Drug Resistance Mechanisms Epigenetic Resistance in Cancer Therapy Biomarkers Pharmacogenetics of Cancer Liquid Biopsy Targeted Cancer Therapy Non-coding RNAs Kinase Inhibitors ABC Transporters

Topic: Role and Application of Non-coding RNAs in Anticancer Drug Resistance

A special issue of Cancer Drug Resistance

ISSN 2578-532X (Online)

Submission deadline: 31 Oct 2022

Guest Editor(s)

  • Dr. Erik A. C. Wiemer
    Department of Medical Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, the Netherlands.

    Website | E-mail

Special Issue Introduction

Anticancer drug resistance remains a major impediment to the successful treatment of cancer. Over the years, specific cell types, multiple genes, and biochemical pathways have been reported to contribute to the process of resistance. Recently, non-coding RNAs such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) were implicated as important mediators of drug-resistant phenotypes in many different cancers. Non-coding RNAs constitute powerful biomolecules, and numerous miRNAs and lncRNAs have been identified that modulate the sensitivity of cancer cells for specific anticancer drugs. In-depth studies of these RNAs and the genes and biochemical pathways they regulate reveal novel and important mechanisms of resistance that may be inhibited to prevent or overcome resistance. Moreover, specific miRNAs or lncRNAs may be instrumental as biomarker signaling drug resistance or can be exploited as a therapeutic target or anticancer agent. This special issue aims to highlight the unique functional involvement of non-coding RNAs in anticancer drug resistance and their use as a biomarker and therapeutic target in this setting. The main challenge for the near future is how to use these novel insights to reverse anticancer drug resistance and improve chemotherapy for the cancer patient.

Submission Deadline

31 Oct 2022

Submission Information

Articles of special issue are free of charge for article processing.
For Author Instructions, please refer to
For Online Submission, please login at
Submission Deadline: 31 Oct 2022
Contacts: Belinda Zhang, Assistant Editor,

Published Articles

© 2016-2023 OAE Publishing Inc., except certain content provided by third parties